Metagenomics

Signal vs. noise: how to analyze the microbiome and make progress on antimicrobial resistance

In silico benchmarking of metagenomic tools for coding sequence detection reveals the limits of sensitivity and precision

BACKGROUND: High-throughput sequencing can establish the functional capacity of a microbial community by cataloging the protein-coding sequences (CDS) present in the metagenome of the community. The relative performance of different computational …